LCMS
UNIQUE SOLUTION FROM ONE COMPANY
Zivak Technologies is an international special company providing ready to use LC-MS/MS and HPLC analysis kits in the clinical diagnostic field. The Research & Development Company also supplies its own fully automated sample preparation and injection systems which enables laboratories around the globe to make efficient use of their chromatography instruments as well as their employees in a fast, accurate and cost efficient way.
SUMMARY AND EXPLANATION
Vitamin D, commonly known as the “sunshine vitamin”, is essential for maintaining calcium metabolism and bone health. The major physiologic function of Vitamin D is to maintain the blood calcium and phosphorus levels within the normal range in order to maintain metabolic functions that are essential for most life processes, Vitamin D3 and Vitamin D2 are metabolized to 25-OH-Vitamin D3 and 25-OH-Vitamin D2 in the liver by the 25-OHase enzyme. The quantitation of these metabolites is widely used for determining of vitamin D status in human. The Vitamin D status has a clinical significance in a variety of disorders which are related to hormones. The measurements of the serum concentration of 25-OH-Vitamin D3 and 25-OH-Vitamin D2 have been used for differential diagnosis of hypocalcemic and hypercalcemic metabolic bone disorders
Catecholamines are hormones produced by the adrenal glands, which are found on top of the kidneys. They are released into the blood during times of physical or emotional stress. The major catecholamines are dopamine, norepinephrine, and epinephrine. The measurements of catecholamines are important for determination of pheochromocytomas in symptomatic patients like patients with persistent hypertension. It is also used in order to help monitor for recurrence when a pheochromocytoma has been discovered and removed. Zivak Catecholamines LC-MS/MS Analysis Kit was developed for accurate analysis of Epinephrine, Norepinephrine and Dopamine in urine samples.